You lose the use of your Super powers under certain circumstances. What triggers this varies from super to super. When en triggered, it is as if you didn't have the schtick at all; it simply fails. Circumstances are usually defined by your origin, usually exposure to whatever made a super in the first place.
Normally, this applies to five of your Super powers. If you have more than five Super powers, it can apply to all of them as an extra limitation.